10 results
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Rheumatology • ... Anti-cardiolipin (aCl ... Anti-centromere, Scl ... #Rheumatology # ... #associations #table
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Autoantibodies and ... syndrome Anti-Scl ... Goodpasture's syndrome #Autoantibodies ... diseases #diagnosis #table ... #rheumatology #
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... ) 30-45% Differential ... Systemic #Lupus #Erythematosus ... #Diagnosis #autoantibodies ... #rheumatology
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
- Markers and Differential ... CD23, o CML ... Amy Chung, MD, MSc ... Blood #Disorders #hematology ... #Markers #Differential
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
(ACLE) • Erythematous ... • Anti-Ro/SSA autoantibodies ... permanent alopecia Differential ... La, anti-Jo-1, SCL ... #Diagnosis #Rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
months) and of autoantibodies ... Systemic Lupus Erythematosus ... sle #comparison #table ... #rheumatology # ... diagnosis #management
Blood Product Components, Contents, Volume and Shelf Life

Whole blood (autologous or directed donations) - RBC and
with about 25 mL ... plasma and 100 mL ... Plasma proteins, all ... Contents #Volume #Hematology ... #Management #Table
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
(HCV) • CLL & MBL ... macular Vasculitis) Autoantibodies ... Evans • ITP • Cl-NH ... Paraproteinemias #Hematology ... #Monoclonal #Differential
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... classical HL (MCHL ... Immunohistochemical studies (to differentiate ... classification #hematology ... #oncology #management
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
without these autoantibodies ... with edema • Erythematous ... dorsal part of the MCP ... Dermatomyositis #diagnosis #management ... #rheumatology #