20 results
Immunosuppression in Transplantation
Induction (I):
 - Basiliximab (Simulect)
 - Alemtuzumab (Campath)
 - Rituximab
 - Anti-Thymocyte Globulin (ATG)
Induction
Immunosuppressive #Medications ... #Pharmacology #Table ... #Drugs #Induction ... #Maintenance #Management ... #Nephrology #Renal
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
syndrome - Na-K-2Cl ... barrtin (recruits Cl ... Thiazide-sensitive Na—Cl ... Defects #Kidney #Nephrology ... #Differential #Table
Drug Induced Kidney Injury
 • Pre-Renal: NSAIDS, CNI, ACEI/ARB, IL-2 therapy, Diuretics CAR-T therapy
 • Osmotic
Drug Induced Kidney ... Injury • Pre-Renal ... Membranous GN, MCD ... diagnosis #algorithm #nephrology ... #Medications
Compelling and Possible Contraindications to Antihypertensive Drugs
Diuretics (thiazides)
 - Gout
 - Metabolic syndrome, Glucose intolerance, Pregnancy,
ARB, diabetes) ACE ... Hyperkalemia, Bilateral renal ... Hyperkalemia, Bilateral renal ... failure - Co-medication ... contraindications #table
Vancomycin Associated Acute Kidney Injury

 • Drug induced acute kidney injury is generally defined as a
Kidney Injury • Drug ... increase of 44 mol ... particularly underlying renal ... toxicology #diagnosis #management ... #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
reactions Common Drugs ... • NSAIDs • ACE ... deficiency • Renal ... Medications 2. ... potassium #high #nephrology
Continuous Renal Replacement Therapy (CRRT) - Overview
Types of CRRT
 • CVVHD - Continuous Veno-Venous hemodialysis -
Continuous Renal ... dialysis dose = 20-25 mL ... 4K, 2K, or 0K (all ... #Continuous #Renal ... #Nephrology #Management
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
reactions Common Drugs ... • NSAIDs • ACE ... deficiency • Renal ... Medications 2. ... potassium #high #nephrology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
irrigation • Management ... Inhibitors of Na+K+2Cl ... Excretion #Diuresis #Nephrology ... #Pharmacology #Medications ... #Table
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Framework and Management ... - Toxins - Drugs ... urine output: 200 ml ... per day until stable ... causes #treatment #nephrology