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diagnosis nephrology differential pharmacology treatment causes hyperkalemia anesthesia checklist intraoperative workup high neurology rhabdomyolysis algorithm anaphylaxis antihypertensive bloodpressure continuous contraindications
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... Angiotensin-converting enzyme (ACE ... • Exogenous (KCL ... #pharmacology #potassium ... #medications #druginduced
Immunosuppression in Transplantation Induction (I): - Basiliximab (Simulect) - Alemtuzumab (Campath) - Rituximab - Anti-Thymocyte Globulin (ATG) Induction
Immunosuppressive #Medications ... #Pharmacology #Table ... #Drugs #Induction ... #Maintenance #Management ... #Nephrology #Renal
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
reactions Common Drugs ... • NSAIDs • ACE ... • Recent IV potassium ... Medications 2. ... diagnosis #causes #potassium
Compelling and Possible Contraindications to Antihypertensive Drugs Diuretics (thiazides) - Gout - Metabolic syndrome, Glucose intolerance, Pregnancy,
ARB, diabetes) ACE ... Hyperkalemia, Bilateral renal ... Hyperkalemia, Bilateral renal ... failure - Co-medication ... contraindications #table
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
Diagnosis and Management ... Drugs (Statins), ... Monitor potassium ... per day until stable ... Differential #Diagnosis #Management
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
reactions Common Drugs ... • NSAIDs • ACE ... • Recent IV potassium ... Medications 2. ... diagnosis #causes #potassium
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Framework and Management ... - Toxins - Drugs ... urine output: 200 ml ... Monitor potassium ... per day until stable
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Etiology: • Medications ... Elimination (see Table ... STOP offending medications ... Ca-gluconate or 1g CaCl ... #Treatment #potassium
Continuous Renal Replacement Therapy (CRRT) - Overview Types of CRRT • CVVHD - Continuous Veno-Venous hemodialysis -
Continuous Renal ... dialysis dose = 20-25 mL ... 4K, 2K, or 0K (all ... #Continuous #Renal ... #Nephrology #Management
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
Agents Regulating Renal ... irrigation • Management ... Inhibitors of Na+K+2Cl ... #Pharmacology #Medications ... #Table
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