138 results
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
, others (RNP, aPL ... Antiphospholipid Antibody Syndrome ... Anti-cardiolipin (aCl ... LAC) • Sjogren Syndrome ... Anti-centromere, Scl
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
- Na-K-2Cl cotransporter ... , K channel, Cl ... barrtin (recruits Cl ... Thiazide-sensitive Na—Cl ... alpha-Intercalated cell Cl
Hypokalemia Differential Diagnosis Algorithm
Hypertensive:
 • High Al, Low R - Primary aldosteronism
 • High Al, High
acid, Liddle's Syndrome ... R - Cushing's syndrome ... Normotensive: • UCl ... Post-hypercapnia • UCl ... , Gitelman's syndrome
Hyperviscosity Syndrome - Causes and Treatment

 - Waldenstrom macroglobulinemia (most common) / Plasmapheresis 
 - Multiple
Hyperviscosity Syndrome ... - Causes and Treatment ... transformation (CML ... hyperleukocytosis (AML ... Hyperviscosity #Syndrome
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Angiotensin-converting enzyme (ACE ... • Exogenous (KCL ... pharmacology #potassium #medications
Medications Used in Hypertensive Emergencies
Vasodilators: Hydralazine, Nitroglycerin, Sodium nitroprusside 
Calcium Channel Blockers: Clevidipine, Nicardipine
ß-Blockers: Esmolol, Labetalol,
Medications Used ... Labetalol, Metoprolol ACE ... #Hypertension #Medications ... #Management #Treatment
Summary of Recommendations for the Treatment of Aspergillosis - IDSA Guidelines
 - Invasive syndromes of Aspergillus
Recommendations for the Treatment ... Guidelines - Invasive syndromes ... or colonizing syndromes ... Aspergillosis #Treatment ... pharmacology #dosing #medications
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, CML, AML, APML ... involvement CML ... ↓ LAP Score • CML ... develop leukostasis syndrome ... • Tumor lysis syndrome
Medications associated with neuroleptic malignant syndrome

First-generation and second-generation antipsychotics are dopamine receptor antagonists, which produce a
Medications associated ... neuroleptic malignant syndrome ... after years of treatment ... NeurolepticMalignant #Syndrome ... #Medications #Drugs
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
hyperaldosteronism • Low Urine Cl ... NGT suction, Low Cl ... • High Urine Cl ... , Gitelman Syndrome ... , Liddle syndrome