36 results
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Autoantibodies and their Disease ... Anti-TSHR - Graves' disease ... connective tissue disease ... (TTG) - Celiac disease ... #Associations #diseases
Cutaneous manifestations associated with myelodysplastic syndrome
 • Myeloid hemopathy with the most frequent skin lesions (20%)
most frequent skin ... appearing during the disease ... dermatomyositis, SLE ... #oncology #clinical ... #skin
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Malar rash • SLE ... infection • Lyme disease ... migrans • Lyme disease ... Sarcoidosis • Crohn's disease ... Antiphospholipid-antibody syndrome
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
with more severe disease ... Used to monitor disease ... Associated with skin ... with more severe disease ... #management
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
ULN R - Renal disease ... chain deposition disease ... lymphoproliferative diseases ... and autoimmune diseases ... #oncology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Systemic disease ... Inflammatory eye disease ... • Neurologic Disease ... #diagnosis #management ... #disease
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
IBD, Whipple's disease ... • Whipple's disease ... • Pleural disease ... , Lyme disease, ... Scleroderma Thickened skin
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... - Bone marrow disease ... deficiency • Liver disease ... Von Willebrand disease ... Dermatosis: Schamberg Disease
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Disease Classification ... rheumatologic diseases ... (e.g. thyroid disease ... ) • Kikuchi disease ... • Castleman's disease
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
Involving the Skin ... Secondary: CTD: SLE ... Vasculitis: • Behcet Disease ... • Cogan syndrome ... #dermatology #rheumatology