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diagnosis differential oncology treatment causes algorithm classification disease erythematosus lupus mcv mds monoclonal neurology renal sle systemic activation aplastic atlas
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Framework for Anemia ... thalassemia • Anemia ... Hypothyroidism, Myelodysplastic ... syndrome - Dr ... diagnosis #causes #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic ... Syndrome (MD) - ... cytopenias (usually anemia ... #Syndrome #MDS ... #treatment #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
malignancies • Anemia ... vera (PV) • Myelodysplastic ... syndrome • Myelofibrosis ... myeloid leukemia (CML ... Diagnosis #Causes #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Corpuscular Volume (MCV ... Hypothyroidism • Myelodysplasia ... #Anemia #MCV ... Algorithm #Causes #Hematology
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
vasculitis • Hematologic ... Abnormalities: macrocytic anemia ... multiple myeloma, myelodysplastic ... criteria for 1) hematologic ... Autoinflammatory #Somatic #rheumatology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Corpuscular Volume (MCV ... Dysplastic • Myelodysplastic ... Syndromes Macrocytosis ... Algorithm #Causes #Hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Iron-deficiency anemia ... Liver diseases, Myelodysplastic ... syndrome, Increased ... Hemolytic uremic syndrome ... #differential #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
blood cell count (anemia ... • Aplastic Anemia ... Myelogenous Leukemia (CML ... Megaloblastic Anemia ... #hematology #oncology
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Disorders - Myelodysplastic ... Pelger-Huet, Macrocytic anemia ... CD23, o CML ... Amy Chung, MD, MSc ... Blood #Disorders #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... • Hypocellular myelodysplastic ... syndrome (MDS) ... #oncology #hematology ... #diagnosis #management
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