116 results
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... • Lupus (SLE): ... Antiphospholipid Antibody Syndrome ... LAC) • Sjogren Syndrome ... Autoantibodies #Rheumatology
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Disease Associations ANA ... Anti-Scl-70 - Scleroderma ... La) - Sjogren's syndrome ... Goodpasture's syndrome ... diagnosis #table #rheumatology
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Measurement in SLE ... and probably < ... #Measurement #SLE ... #rheumatology # ... levels #lupus #management
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Kasabach-Merritt syndrome ... Associated - SLE ... Differential #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Autoimmune • ITP • SLE ... Non-lmmune: • HELLP Syndrome ... Diagnosis #Algorithm #Causes ... #Hematology
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Hypereosinophilia and ... Hypereosinophilic Syndrome ... • Diagnosis and ... #HES #Hematology ... eosinophils #diagnosis #management
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Causes of Thrombocytosis ... Myelodysplastic syndrome ... myeloid leukemia (CML ... Differential #Diagnosis #Causes ... #hematology #secondary
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
/dL or CC < 40 ml ... Causes of false- ... amyloidosis Other causes ... plasmacytoma, POEMs syndrome ... MGUS #diagnosis #hematology
Algorithm for the Evaluation and Management of Sickle Cell Crises
Clinical Manifestations and Management

#Diagnosis #Management #Hematology #SickleCell
the Evaluation and ... Management of Sickle ... Cell Crises Clinical ... Manifestations and ... #Management #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Causes of Thrombocytopenia ... function test, ANA ... (e.g., SLE), anti-phospholipid ... changes), high MCV ... #Workup #hematology