16 results
Diuretics sites of action on the nephron
1) Acetazolamide (carbonic anhydrase inhibitor)
2) Osmotic diuretics (e.g. mannitol)
3) Loop
Diuretics sites ... Metolazone) 5) Potassium-sparing ... diuretics (e.g. ... #pharmacology # ... nephrology #medications
Summary of Diuretic Agents 
Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction
CARBONIC ANHYDRASE
Summary of Diuretic ... Chlorthalidone POTASSIUM-SPARING ... Tolvaptan #Diuretics ... #Medications #Pharmacology ... summary #table #nephrology
Pharmacokinetics of commonly used diuretics medications in CKD, Cirrhotic Ascites, and Heart Failure
 • Furosemide
 •
commonly used diuretics ... medications in ... Spironolactone MCW ... Nephrology @MCW_Nephrology ... pharmacology #Pharmacokinetics
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Thyrotoxicosis Medications ... Renal Losses ... • Discontinued diuretic ... Diagnosis #Algorithm #nephrology ... #low #potassium
Diuresis in Critical Care - Achieving a Negative Fluid Balance
Advantages Of A Negative Fluid Balance:
 •
TO PO • USE HIGH ... CONCENTRATION MEDICATIONS ... ) to normalize Potassium ... especially in high ... Early nephrologv
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Inhibitors of Na+K+2Cl ... ; High-Ceiling Diuretics ... #Diuresis #Nephrology ... #Pharmacology # ... Medications #Table
Drugs associated with hypokalemia and hypomagnesemia

Hypokalemia
- Shift from extracellular fluid to intracellular fluid compartment
  -
- Insulin (high ... foscarnet - Diuretics ... and other loop diuretics ... hypomagnesemia #Medications ... differential #diagnosis #nephrology
Causes of Hypomagnesemia
Redistribution:
 - IV glucose
 - Correction of diabetic ketoacidosis
 - IV hyperalimentation
 - Refeeding
(steatorrhea) Renal ... - Potassium depletion ... Tubulointerstitial renal ... #differential #medications ... #drugs #pharmacology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
phlebotomy High ... • K sparing diuretics ... • Recent IV potassium ... Medications 2. ... #high #nephrology
Drug Induced Kidney Injury
 • Pre-Renal: NSAIDS, CNI, ACEI/ARB, IL-2 therapy, Diuretics CAR-T therapy
 • Osmotic
Injury • Pre-Renal ... IL-2 therapy, Diuretics ... Membranous GN, MCD ... diagnosis #algorithm #nephrology ... #Medications