15 results
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
Amy Chung, MD, MSc ... Anticoagulants #Medications ... #Pharmacology # ... Mechanisms #DOAC #Hematology
Drug Induced Kidney Injury
 • Pre-Renal: NSAIDS, CNI, ACEI/ARB, IL-2 therapy, Diuretics CAR-T therapy
 • Osmotic
Membranous GN, MCD ... Interstitial: PPIs, Antibiotics ... tubular injury: Antibiotics ... #KidneyInjury #differential ... algorithm #nephrology #Medications
Common Medications Known to Prolong QTc
Antiarrhythmics - Amiodarone, sotalol, flecainide, quinidine, dronedarone, dofetilide
Vasopressors/inotropes - Epinephrine, norepinephrine,
Common Medications ... , venlafaxine Antibiotics ... #Prolongation #Medications ... #Causes #differential ... #diagnosis #pharmacology
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
concentration: > 750ng/mL ... probably < 1500ng/mL ... Best indications ... Measurement #SLE #rheumatology ... #pharmacology #
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
• Exogenous (KCL ... #hyperkalemia #differential ... pathophysiology #pharmacology ... #potassium #medications
Causes of Isolated Neutropenia - Differential Diagnosis Algorithm
Congenital
Medications
 • Anticonvulsants
 • Antibiotics
 • Antithyroid
 • Antihypertensive
Neutropenia - Differential ... Algorithm Congenital Medications ... Anticonvulsants • Antibiotics ... #Neutropenia #Differential ... Algorithm #Causes #Hematology
Drug-Induced Seizures - OTIS-CAMPBELL

O - Organophosphate, oral hypoglycemics, opioid
T - TCA, theophylline
I - Isoniazid, Insulin
S -
anticholinergics, amantadine, antibiotics ... Induced #Seizures #Medication ... #Causes #Differential ... #Pharmacology #
Drug Induced Uveitis - Medications Associated with Uveitis

#DrugInduced #Uveitis #Medications #Rheumatology #Pharmacology #Differential #Causes
Induced Uveitis - Medications ... DrugInduced #Uveitis #Medications ... #Rheumatology # ... Pharmacology #Differential
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
- Markers and Differential ... CD23, o CML ... Amy Chung, MD, MSc ... Blood #Disorders #hematology ... #Markers #Differential
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... family history - Medications ... changes), high MCV ... Platelet #Disorders #Differential ... Causes #Workup #hematology