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differential management treatment algorithm hyperkalemia hypokalemia hypomagnesemia neurology high hypomg low rhabdomyolysis serotonin acromegaly alkalosis ammonia chloride diuresis diuretics drug
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... #differential #diagnosis ... #pathophysiology ... #pharmacology # ... potassium #medications
Causes of Hypomagnesemia Redistribution: - IV glucose - Correction of diabetic ketoacidosis - IV hyperalimentation - Refeeding
Causes of Hypomagnesemia ... osmotic diuresis - Potassium ... #diagnosis #differential ... #medications #drugs ... #pharmacology #
Hypokalemia Differential Diagnosis Algorithm Hypertensive: • High Al, Low R - Primary aldosteronism • High Al, High
Hypokalemia Differential Diagnosis ... Normotensive: • UCl ... #Differential #Diagnosis ... #Algorithm #nephrology ... #causes #low #potassium
Serotonin Syndrome Drug Precipitants and Pharmacology ↑ Serotonin Formation: Tryptophan, Oxitriptan ↑ Serotonin Release: Amphetamines, Cocaine, Mirtazapine ↑ Serotonin
Serotonin Syndrome ... Drug Precipitants ... and Pharmacology ... medications #causes ... #differential #diagnosis
Drugs associated with hypokalemia and hypomagnesemia Hypokalemia - Shift from extracellular fluid to intracellular fluid compartment -
Drugs associated ... renal Fanconi syndrome ... hypomagnesemia #Medications ... #differential #diagnosis ... #nephrology #Causes
Causes of Seizures - Differential Diagnosis Algorithm Unprovoked - Epilepsy: • Focal: Simple, Complex • Generalized: Absence,
Causes of Seizures ... vasoconstriction syndrome ... Toxic: Alcohol, Medication ... , Recreational drugs ... #neurology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
reactions Common Drugs ... - Tumor lysis syndrome ... Medications 2. ... #causes #potassium ... #high #nephrology
Causes of Hypomagnesemia • Redistribution: IV glucose, Correction of diabetic ketoacidosis, IV hyperalimentation, Refeeding after starvation,
Causes of Hypomagnesemia ... osmotic diuresis, Potassium ... renal disease • Drugs ... #differential #diagnosis ... #nephrology #magnesium
Schematic representation of the major sources of ammonia production and its excretory pathway (GI = gastrointestinal,
ileal conduit - Medications ... Multiple myeloma, CML ... rare): - Reye syndrome ... deficiency #Ammonia #Pathophysiology ... #Differential #Diagnosis
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
reactions Common Drugs ... - Tumor lysis syndrome ... Medications 2. ... #causes #potassium ... #high #nephrology
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