65 results
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
• Exogenous (KCL ... #hyperkalemia #differential ... #diagnosis #pathophysiology ... #pharmacology #
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
transporter Bartter syndrome ... limb Gitelman syndrome ... tubule Liddle syndrome ... deficiency Nephrogenic syndrome ... Nephrology #Diagnosis #Differential
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Metabolic Alkalosis - Differential ... • High Urine Cl ... , Gitelman Syndrome ... , Liddle syndrome ... Metabolic #Alkalosis #Differential
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
Metabolic Alkalosis - Differential ... • High Urine Cl ... , Gitelman Syndrome ... , Liddle syndrome ... Metabolic #Alkalosis #Differential
Raynaud Phenomenon Differential Diagnosis:

Rheumatologic

 - MCC systemic sclerosis, RA, SLE, Sjogren syndrome, Antisynthetase syndrome, MCTD
Heme

 -
Raynaud Phenomenon Differential ... Rheumatologic - MCC ... , SLE, Sjogren syndrome ... Antisynthetase syndrome ... #Differential
Hypokalemia Differential Diagnosis Algorithm
Hypertensive:
 • High Al, Low R - Primary aldosteronism
 • High Al, High
Hypokalemia Differential ... acid, Liddle's Syndrome ... Normotensive: • UCl ... Post-hypercapnia • UCl ... #Hypokalemia #Differential
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
• Serotonin Syndrome ... SSRI Withdrawal Syndrome ... Serotonin #Inhibitors #Pathophysiology ... #Pharmacology #
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Hypokalemia - Differential ... - Refeeding Syndrome ... #Hypokalemia #Differential ... potassium #low #pathophysiology
Purple Urine Bag Syndrome
Chronic, indwelling catheter + bacteriuria (Providencia, Klebsiella, E.coli*) + alkaline urine
Tryptophan → Indoxyl
Purple Urine Bag Syndrome ... Purple #Urine #Bag #Syndrome ... #PUBS #pathophysiology ... clinical #photo #differential
Mechanisms of nephron damage in cardiorenal syndrome
 • Increased renal interstitial pressure
 • Hypoperfusion
 • Reduced
in cardiorenal syndrome ... release • ↓ Cl ... #cardiorenal #syndrome ... #Mechanisms #pathophysiology