23 results
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
• Exogenous (KCL ... #hyperkalemia #differential ... pathophysiology #pharmacology ... #potassium #medications
Hypokalemia Differential Diagnosis Algorithm
Hypertensive:
 • High Al, Low R - Primary aldosteronism
 • High Al, High
Hypokalemia Differential ... Normotensive: • UCl ... #Hypokalemia #Differential ... Diagnosis #Algorithm #nephrology ... #causes #low #potassium
Drug Induced Kidney Injury
 • Pre-Renal: NSAIDS, CNI, ACEI/ARB, IL-2 therapy, Diuretics CAR-T therapy
 • Osmotic
Membranous GN, MCD ... Interstitial: PPIs, Antibiotics ... tubular injury: Antibiotics ... #KidneyInjury #differential ... diagnosis #algorithm #nephrology
Algorithm for the Treatment of Uremic Pruritus
Nonpharmacologic Treatments:
 • Daily topical emollient
 • Avoidance of extremes
Algorithm for the Treatment ... Evidence-Based Off-Label Pharmacologic ... Treatments of Uremic ... nalfurafine 2.5 mcg ... #management #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... • Recent IV potassium ... Beta blockers • Antibiotics ... #hyperkalemia #differential ... #high #nephrology
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
the basis of the potassium-to-creatinine ... • Low Urine Cl ... hypokalemia #urine #potassium ... #differential # ... algorithm #diagnosis #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... • Recent IV potassium ... Beta blockers • Antibiotics ... #hyperkalemia #differential ... #high #nephrology
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
Diuretics - Pharmacology ... • Inhibit Na+ Cl ... Piretanide Potassium ... #Diuretics #Pharmacology ... #nephrology #conversion
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
Potassium Binders ... cyclosilicate #Potassium ... #Hyperkalemia #treatment ... #pharmacology # ... table #comparison #nephrology
Vancomycin Associated Acute Kidney Injury

 • Drug induced acute kidney injury is generally defined as a
increase of 44 mol ... • Treatment includes ... Vancomycin #AKI #pharmacology ... diagnosis #management #nephrology