18 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Secondary ... Clinically Relevant HES ... Diagnosis and Treatment ... #HES #Hematology ... #eosinophilia #
Hypereosinophilia Syndrome (HES) - Diagnosis and Management
Definition: An absolute eosinophil count (AEC) greater than 1500 and
Hypereosinophilia Syndrome ... Secondary Causes ... Hypereosinophilia #Syndrome ... #HES #eosinophilia ... #diagnosis #hematology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Testing Algorithm ... • Screen for secondary ... causes of eosinophilia ... (common causes ... glucocorticoid treatment
Causes of Eosinophilia - Differential Diagnosis
Bugs:
 - Fungus (aspergillosis)
 - Viral (HIV)
 - Ectoparasites (scabies, myiasis)
Causes of Eosinophilia ... Primary: - CML ... Mastocytosis - Acute ... Hypereosinophilic Syndrome ... #hematology
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Causes of Thrombocytosis ... Thrombocytosis): • Acute ... Myelodysplastic syndrome ... myeloid leukemia (CML ... #hematology #secondary
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... - AKI Workup Algorithm ... osmolarity If cause ... , eosinophiluria ... pressure • TTP / HUS
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... transformation to acute ... only curative treatment ... #hematology #oncology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Causes of Anemia ... Corpuscular Volume (MCV ... Hypersplenism • Secondary ... Normal RBCs • Acute ... #Causes #Hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
leakage of RBC's secondary ... Kasabach-Merritt syndrome ... - APLS • Acute ... Gardner-Diamond syndrome ... #rheumatology #
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... • (Peripheral eosinophilia ... • Tumor lysis syndrome ... bone marrow and secondary ... #Oncology #Diagnosis