13 results
Validation of the “Step-by-Step” Approach in the Management of Young Febrile Infants
Visual Abstract by Dr. Kirsty
Approach in the Management ... pubmed/27382134 #EBM ... #Peds #Pediatrics ... Febrile #Infant #Risk ... Stratification #Fever
“Step by Step” – the new kid on the block – aims to risk stratify this
investigations and treatments ... an infant with fever ... Procalcitonin <0.5 ng/mL ... #Diagnosis #Management ... #Pediatrics #Peds
Treatment Schema for Standard-Risk Acute Lymphoblastic Leukemia
Induction: 
 • Vincristine, Steroid (dexamethasone), L-Asparaginase, Intrathecal (IT) methotrexate
Consolidation
for Standard-Risk ... Cytarabine #ALL ... #timeline #oncology ... #pediatrics #peds ... #management
Asthma management- what is the evidence? 

MDI vs. Nebulization of Beta agonist 
 - Has been
Asthma management ... for children of all ... Fewer dexamethasone ... #ebm #pulmonary ... #peds #pediatrics
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
Patient risk stratification ... treatment of cancer-associated ... thrombosis; PE = pulmonary ... Anticoagulation #Management ... #Hematology #Oncology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
) B symptoms → fevers ... chemotherapy for low-risk ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc ... #diagnosis #management
The Febrile Infant Step-by-Step Algorithm
This is an algorithm developed by European emergency physicians to identify low-risk
empiric antibiotic treatment ... 46.9% #Diagnosis #EBM ... #Management #Pediatrics ... #Peds #Febrile ... Stratification #Fever
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Attempt if high risk ... Subacute-Acute: • Common: fever ... Imaging: CXR- pulmonary ... APML #diagnosis #management ... #hematology #oncology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... Unknown cause Treatment ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary ... #rheumatology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
syndrome): - Hematologic ... mg/dL or > 25 % rise ... fluids (200–300 mL ... ± tocilizumab; call ... renal failure, pulmonary