15 results
management rheumatology dermatology oncology antibiotics disease hemeonc hemophagocytic hlh infant lp lymphohistiocytosis pediatrics risk stepbystep stratification sweet activation acute adult
Erythematous Rashes - THE ALGORITHMIC APPROACH Characterized by diffuse redness of the skin due to capillary congestion, erythematous
Erythematous Rashes - THE ALGORITHMIC ... and toxic shock syndrome ... #Diagnosis #Dermatology ... Erythematous #Rash #Algorithm ... #Nikolsky #Febrile
“Step by Step” – the new kid on the block – aims to risk stratify this
investigations and treatments ... Procalcitonin <0.5 ng/mL ... CRP < 20 mg/L #Diagnosis ... Management #Pediatrics #Peds ... #Febrile #Infant
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Subacute-Acute: • Common: fever ... Rare: DAH, acute febrile ... Imaging: CXR- pulmonary ... #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... acute or subacute febrile ... following: • Fever ... Ferritin >500 ng/mL ... #hematology
Diagnostic Criteria for Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis) Major criteria 1. Abrupt onset of tender
Diagnostic Criteria ... for Sweet Syndrome ... (Acute Febrile ... Fever, temperature ... Excellent response to treatment
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- 80% have fever ... organ damage • Treatment ... : - If febrile ... #TLS #diagnosis ... #management #hematology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Acute febrile ... , breast CA - Hematologic ... Leukemia cutis Diagnosis ... Treatment: - Systemic ... #diagnosis #dermatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
- Nonremitting fever ... 5000 to 10,000 ng/mL ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
extremities during febrile ... Ferritin >3000 ng/mL ... Treatment - Mild ... : NSAIDS Treatment ... #rheumatology #
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
work-up - If febrile ... ): - Hematologic ... fluids (200–300 mL ... renal failure, pulmonary ... Oncology #HemeOnc #Diagnosis
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