13 results
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
Clinical TLS: • AKI ... Treatment of TLS ... hydroxide • Hyperkalemia ... TLS #diagnosis #management ... #oncology
Causes of HyperKalemia - Differential Diagnosis
Increased extracellular K+:
 • Tissue injury
 • Hemolysis
 • Rhabdomyolysis
 •
Causes of HyperKalemia ... - Differential ... Elimination: • AKI ... blockers - MCW ... #HyperKalemia
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... Framework and Management ... • LDH ↑ • Hyperkalemia ... Dialysis for severe hyperkalemia ... #nephrology
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
Kidney Injury (AKI ... Cancer Related • Hypercalcemia ... malignancies Treatment ... #Cancer #Oncology ... #Differential #
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... , RTA Type IV, AI ... emcrit.org/ibcc/hyperkalemia ... of hyperkalemia ... #Hyperkalemia
Tumor Lysis Syndrome
An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
6L/day) • For hyperkalemia ... otherwise treat with "hyperkalemia ... Walid Malki, MD, MS ... Syndrome #TLS #oncology ... #management #UricAcid
Algorithm for Management of Acute and Chronic Hyperkalemia
Acute Hyperkalemia:
 - IV calcium (10 mL of 10%)
Acute and Chronic Hyperkalemia ... Acute Hyperkalemia ... binders Chronic Hyperkalemia ... optimization) #Hyperkalemia ... Acute #Chronic #treatment
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Rhabdomyolysis - Differential ... Diagnosis and Management ... Dermatomyositis) AKI ... Dialysis for severe hyperkalemia ... #Diagnosis #Management
Gitelman Syndrome - Management
Treatment includes
 - Electrolyte replacement - K & Mg, preferably Cl salts
Gitelman Syndrome - Management ... Treatment includes ... Mg, preferably Cl ... In persistent hypokalemia ... #Treatment #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Family history of hypokalemia ... • Unexplained hypokalemia ... pressure Labs: • Hypokalemia ... ratio 0.5%) Differential ... #Hypokalemia