6102 results
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
Significance (MGUS ... Prevalence M > F MGUS ... IgM MGUS: • Serum ... constitutional symptoms ... Significance #hematology #diagnosis
Complications of Monoclonal Gammopathy of Undetermined Significance (MGUS)
Fracture, Osteoporosis
 - Increased osteoclast activity and bone resorption
Significance (MGUS ... treatment of infective symptoms ... high-risk situations #MGUS ... Complications #diagnosis
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
(Cold-induced symptoms ... Diagnosis: • hemolytic ... Differential Diagnosis ... significance (MGUS ... rewarming • Symptoms
Monoclonal Gammopathy Testing
Strengths, Weaknesses and Accuracy Compared
 - SPEP 
 - IFE 
 - FLC
Testing #Protein #Diagnosis ... #MGRS #MGUS #SPEP
Suggested algorithm for bone marrow biopsy and skeletal imaging in patients with monoclonal gammopathy of undetermined
significance (MGUS ... 1.5 gm/dL) IgM MGUS ... , low-risk MGUS ... 8) light-chain MGUS ... Biopsy #algorithm #diagnosis
Suggested algorithm for follow-up of monoclonal gammopathy of undetermined significance (MGUS)
Mayo Clinic Risk Stratification Model. CBC,
significance (MGUS ... monoclonal #gammopathy #MGUS ... Followup #algorithm #diagnosis
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Significance (MGUS ... - Differential Diagnosis ... Renal-centered (ie "MGRS ... #Significance #MGUS ... #Differential #Diagnosis
MGRS - Monoclonal Gammopathy of Renal Significance 

#MGRS #Monoclonal #Gammopathy #Renal #Significance #Diagnosis #Pathology
MGRS - Monoclonal ... Significance #MGRS ... #Significance #Diagnosis
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• MM • WM • MGUS ... • MGCSMGRS ... Dermato-neuro syndrome) MGRS ... #Differential #Diagnosis
Eosinophilic Esophagitis (EoE) - Spectrum of Response
Non-response:
 • Histology: Persistent eosinophilia, ≥ 15 eos/hpf
 • Symptoms:
15 eos/hpf • Symptoms ... : Persistent symptoms ... decrease in a symptom ... : Decreased symptoms ... EoE #Response #diagnosis