111 results
Monoclonal Gammopathy Testing
Strengths, Weaknesses and Accuracy Compared
 - SPEP 
 - IFE 
 - FLC
Testing #Protein #Diagnosis ... #MGRS #MGUS #SPEP
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... Significance (MGUS ... - Differential Diagnosis ... Renal-centered (ie "MGRS ... #Significance #MGUS
MGRS - Monoclonal Gammopathy of Renal Significance 

#MGRS #Monoclonal #Gammopathy #Renal #Significance #Diagnosis #Pathology
MGRS - Monoclonal ... Significance #MGRS ... #Significance #Diagnosis
Suggested algorithm for bone marrow biopsy and skeletal imaging in patients with monoclonal gammopathy of undetermined
significance (MGUS ... 1.5 gm/dL) IgM MGUS ... , low-risk MGUS ... whom there are no clinical ... Biopsy #algorithm #diagnosis
Suggested algorithm for follow-up of monoclonal gammopathy of undetermined significance (MGUS)
Mayo Clinic Risk Stratification Model. CBC,
significance (MGUS ... ) Mayo Clinic Risk ... monoclonal #gammopathy #MGUS ... Followup #algorithm #diagnosis
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• MM • WM • MGUS ... • MGCSMGRS ... Dermato-neuro syndrome) MGRS ... #Differential #Diagnosis
Rouleaux formation is common in IgM gammopathy and may be particularly striking

Genevieve Crane, MD, PhD@evemariecrane

#Rouleaux #formation
IgM #gammopathy #MGUS ... #Clinical #Pathology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
Significance (MGUS ... Prevalence M > F MGUS ... IgM MGUS: • Serum ... Light-Chain MGUS ... not defined #MGUS
Amyloidosis Diagnosis
1) Patient presentation
 • Cardiac-specific signs of amyloidosis: Diastolic heart failure, Heart failure with preserved
Amyloidosis Diagnosis ... significance (MGUS ... neuropathy, atypical MGUS ... #Amyloidosis #Diagnosis
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
- Differential Diagnosis ... Myeloma • MGUS ... #Differential #Diagnosis