21 results
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Significance (MGUS ... Diagnosis Neurologic-Centered ... Renal-centered (ie "MGRS ... #Significance #MGUS ... Diagnosis #hematology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• MM • WM • MGUS ... • MGCSMGRS ... et diutinum Neurologic ... Dermato-neuro syndrome) MGRS ... #Diagnosis #Oncology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
Significance (MGUS ... Prevalence M > F MGUS ... IgM MGUS: • Serum ... constitutional symptoms ... Light-Chain MGUS
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
lymphoproliferative disorder ... Viral Infection Clinical ... younger pts) Differential ... significance (MGUS ... hemolytic #anemia #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential ... Diagnosis and Workup ... pylori test (GI symptoms ... (CVID, WAS), (neurologic ... #Differential #
Complications of Monoclonal Gammopathy of Undetermined Significance (MGUS)
Fracture, Osteoporosis
 - Increased osteoclast activity and bone resorption
Significance (MGUS ... treatment of infective symptoms ... rituximab (in clinical ... high-risk situations #MGUS ... Complications #diagnosis
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders ... - Differential ... Diagnosis Algorithm ... pattern of spread, B symptoms ... Amy Chung, MD, MSc
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
impairment, Mood disorder ... patients with clinically ... stimulation Clinical ... objective evidence of neurologic ... #management #neurology
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
Spinal Cord Disorders ... - Differential ... Diagnosis Framework ... neurological lesion: Clinical ... #diagnosis #neurology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
in HIV / AIDS - Differential ... Diagnosis Framework ... should be based on clinical ... Suspect in movement disorders ... CNS #Infections #differential