13 results
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Monoclonal Gammopathy ... (MGUS) - Differential ... Renal-centered (ie "MGRS ... #Gammopathy #Clinical ... #Significance #MGUS
Suggested algorithm for follow-up of monoclonal gammopathy of undetermined significance (MGUS)
Mayo Clinic Risk Stratification Model. CBC,
significance (MGUS ... ) Mayo Clinic Risk ... #monoclonal #gammopathy ... #MGUS #Followup ... #algorithm #diagnosis
Suggested algorithm for bone marrow biopsy and skeletal imaging in patients with monoclonal gammopathy of undetermined
significance (MGUS ... , low-risk MGUS ... whom there are no clinical ... #monoclonal #gammopathy ... algorithm #diagnosis
Complications of Monoclonal Gammopathy of Undetermined Significance (MGUS)
Fracture, Osteoporosis
 - Increased osteoclast activity and bone resorption
Significance (MGUS ... rituximab (in clinical ... high-risk situations #MGUS ... #Monoclonal #Gammopathy ... Complications #diagnosis
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
Monoclonal Gammopathy ... Significance (MGUS ... IgM MGUS: • Serum ... constitutional symptoms ... #Monoclonal #Gammopathy
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• MM • WM • MGUS ... • MGCSMGRS ... • Heavy Chain disease ... Dermato-neuro syndrome) MGRS ... #Diagnosis #Oncology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral Infection Clinical ... gammopathy of undetermined ... significance (MGUS ... hemolytic #anemia #hematology ... #diagnosis
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
LC deposition disease ... tubulopathy • Monoclonal ... gammopathy of renal ... significance (MGRS ... #Differential #Diagnosis
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
Multiple Myeloma and Monoclonal ... ULN R - Renal disease ... chain deposition disease ... #Gammopathies #MGUS ... #diagnosis #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Causes of Monoclonal ... : • MGUS • Multiple ... • Heavy chain disease ... #differential #diagnosis ... #hematology