26 results
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... Significance (MGUS ... Renal-centered (ie "MGRS ... Monoclonal #Gammopathy #Clinical ... #Significance #MGUS
Suggested algorithm for bone marrow biopsy and skeletal imaging in patients with monoclonal gammopathy of undetermined
significance (MGUS ... 1.5 gm/dL) IgM MGUS ... , low-risk MGUS ... whom there are no clinical ... algorithm #diagnosis #management
Suggested algorithm for follow-up of monoclonal gammopathy of undetermined significance (MGUS)
Mayo Clinic Risk Stratification Model. CBC,
significance (MGUS ... ) Mayo Clinic Risk ... monoclonal #gammopathy #MGUS ... algorithm #diagnosis #management
Rouleaux formation is common in IgM gammopathy and may be particularly striking

Genevieve Crane, MD, PhD@evemariecrane

#Rouleaux #formation
IgM #gammopathy #MGUS ... #Clinical #Pathology
Complications of Monoclonal Gammopathy of Undetermined Significance (MGUS)
Fracture, Osteoporosis
 - Increased osteoclast activity and bone resorption
Significance (MGUS ... rituximab (in clinical ... high-risk situations #MGUS
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral Infection Clinical ... significance (MGUS
Difficult Airway Algorithm

1. Assess the likelihood and clinical impact of basic management problems: 
 • Difficulty
likelihood and clinical ... impact of basic management ... • Difficult mask ... difficult airway management ... #CriticalCare #Management
Mallet Finger
Absence of a fracture does NOT exclude Mallet finger, the extension function of the DIP
joint needs to be clinically ... fracture • ED Management ... XRay #Diagnosis #Management ... #Orthopedics #MSK
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Multiple Sclerosis (MS ... nearly 3:1 • MS ... patients with clinically ... stimulation Clinical ... sclerosis #diagnosis #management
Bradykinin-mediated Angioedema
Clinical features: Submucosal oedema (face, extremity, genitalia), Laryngeal dyspnea (25% of deaths), Recurrent attacks of
Bradykinin-mediated Angioedema Clinical ... lymphoproliferative disorders (MGUS ... immunology #diagnosis #management