11 results
Monoclonal Gammopathy Testing
Strengths, Weaknesses and Accuracy Compared
 - SPEP 
 - IFE 
 - FLC
Monoclonal Gammopathy ... UPEP / IFE #Monoclonal ... Protein #Diagnosis #MGRS ... #MGUS #SPEP #IFE ... #FLC #Nephrology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
of Clinical Significance ... (MGUS) - Differential ... Diagnosis Neurologic-Centered ... Renal-centered (ie "MGRS ... #Significance #MGUS
Suggested algorithm for follow-up of monoclonal gammopathy of undetermined significance (MGUS)
Mayo Clinic Risk Stratification Model. CBC,
for follow-up of monoclonal ... significance (MGUS ... ) Mayo Clinic Risk ... #monoclonal #gammopathy ... #MGUS #Followup
Suggested algorithm for bone marrow biopsy and skeletal imaging in patients with monoclonal gammopathy of undetermined
significance (MGUS ... 1.5 gm/dL) IgM MGUS ... , low-risk MGUS ... whom there are no clinical ... #MGUS #Biopsy #
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• MM • WM • MGUS ... • MGCSMGRS ... et diutinum Neurologic ... Dermato-neuro syndrome) MGRS ... WAIHA • CAD • PCH
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
- Idiopathic monoclonal ... malignancy (CLL) - Monoclonal ... Viral Infection Clinical ... Such As: • IgM monoclonal ... significance (MGUS
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
tubulopathy • Monoclonal ... significance (MGRS ... Classification #Nephrology
Complications of Monoclonal Gammopathy of Undetermined Significance (MGUS)
Fracture, Osteoporosis
 - Increased osteoclast activity and bone resorption
Complications of Monoclonal ... Significance (MGUS ... Renal disease - Monoclonal ... rituximab (in clinical ... high-risk situations #MGUS
Left Wrist Drop - Radial Nerve Palsy on Physical Examination

Left hand drop due to compression of
radial nerve in its path ... #PhysicalExam #clinical ... #orthopedics #msk ... #sports #neurology
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
patients with clinically ... stimulation Clinical ... FLARE) (85% of pts ... objective evidence of neurologic ... diagnosis #management #neurology