31 results
Allopecia - Differential Diagnosis Framework for Hair Loss

Localized / Focal Hair Loss Pattern:
 • Scarring Alopecia:
Skin Disease: Discoid ... lupus erythematosus ... Trichotillomania, Pressure-induced ... : Lupus erythematosus ... Scaling, pustules, crusts
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm

DIFFUSE
Scarring - Irreversible-biopsy required
 • Lupus
Vitamin A Excess - Drugs ... • Hyperthyroid drugs ... Disease • Discoid ... lupus erythematosus ... Diagnosis #Algorithm #causes
Medications associated with drug-induced lupus

List of Definite and Possible Associated Drugs

#Diagnosis #Pharmacology #Medications #DrugInduced #Lupus #List
associated with drug-induced ... lupus List of ... Definite and Possible ... #Diagnosis #Pharmacology ... #List #Causes #
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... vs SLE Drug Induced ... cases, drug-dependent ... Discontinuation of causal ... Positive in 60-80% of cases
Causes of Pharyngitis - Differential Diagnosis
Infectious:
 • Bacterial: Group A Strep, Group B and C Strep,
Causes of Pharyngitis ... Viruses Autoimmune: Lupus ... formally DRESS), Drug-induced ... agranulocytosis, Drug-induced ... Differential #Diagnosis #Causes
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
: Non-scarring alopecia ... > 0.5 g/24 hr, Class ... , Class Ill or IV ... low C4, Low C3 and ... Erythematosus #diagnosis #rheumatology
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... areas -> Scaring alopecia ... hair follicles -> causes ... follicular plugging -> Discoid ... mechanism) -> Alopecia
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Photosensitivity, Alopecia ... , oral ulcers, Lupus ... Positive in 60-80% of cases ... Management #Summary #rheumatology
Great Mimickers - SHALLOTS Mnemonic

S- Syphilis - Neurosyphilis, aortitis, gummas... Granulomas can form anywhere! Skin, mucosa,
What doesn't HIV cause ... anything L - Lupus ... ulcers, arthritis, alopecia ... pericarditis, pleuritis, drug-induced ... Could be lupus in
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia ... extremities Drug ... Induced Lupus: ... • Antihistone: Drug ... induced SLE •