11 results
ANTIBIOTIC SUSCEPTIBILITIES IN INTENSIVE CARE

Antibiotic spectra made simple(r). Version 2, now updated with new bugs &
with new bugs & drugs ... Susceptibilities #ICU ... CriticalCare #Overview ... #Pharmacology # ... Comprehensive Review
Linezolid (Zyvox) (PO and IV) - Antibiotics Class Overview

Mechanism: Oxazolidinone class –unique ribosomal inhibitor (acts on
Class Overview ... Bacteriostatic agent ... Also has good activity ... infections #Pharmacology ... #Antibiotics #Review
Synercid (Quinupristin/Dalfopristin) (IV) - Antibiotics Class Overview

Mechanism: “Streptogramins”– inhibits sequential steps in ribosomal synthesis
Spectrum: covers MRSA
Dalfopristin) (IV) - Antibiotics ... Class Overview ... arthralgias and lots of drug-drug ... #Pharmacology #Antibiotics ... #Review #Overview
Antifungal Echinocandins  - Antibiotics Class Overview

Mechanism: Inhibit glucan synthesis in fungal cell wall by blocking
synthase à fungicidal agent ... vs Candida -> Drug ... But higher MICs ... Anidulafungin #Pharmacology ... #Antibiotics #Review
Antifungal Polyenes - Amphoterecin B, Abelcet, Ambisome - Antibiotics Class Overview

Mechanism: binds ergosterol in membrane and
Class Overview ... Drug of choice for ... voriconazole is drug ... #Pharmacology #Antibiotics ... #Review #Overview
Vancomycin and Dalbavancin (lipoglycopeptide antibiotics) - Antibiotics Class Overview

Mechanism: Glycopeptide -  inhibits cell wall synthesis
Class Overview ... gram positive agent ... Drug of choice for ... #Pharmacology #Antibiotics ... #Review #Overview
Flutycosine - Antibiotics Class Overview
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Mechanism: 5-FC interferes with DNA and protein synthesis.  Only
Class Overview ... Virtually never used as ... - Drug levels ... #Pharmacology #Antibiotics ... #Review #Overview
Sulfonamides - Antibiotics Class Overview

BACTRIM/SEPTRA (TMP/SMX) - inhibit sequential steps in Folate synthesis --> bacteriostatic

Spectrum: Wide
Class Overview ... apart from other agents ... including PCP PNA (drug ... #Pharmacology #Antibiotics ... #Review #Overview
Tetracyclines – Doxycycline, Tetracycline, Minocycline - Antibiotics Class Overview

- 30S Inhibitors (PO and IV)
Spectrum: Fairly broad
Minocycline - Antibiotics ... Class Overview ... Drug of choice for ... #Pharmacology #Antibiotics ... #Review #Overview
Anti-Pseudomonal - Antibiotics Class Overview

Pseudomonas aeruginosa is a non-fermenting Gram-negative bacillus that inhabits a variety of
Class Overview ... 2nd agent added ... Polymyxin B(IV) #Pharmacology ... #Antibiotics #Review ... #Overview #AntiPseudomonal