10 results
Arachidonic acid pathway and drugs which affect it.

#Pharmacology #Pathophysiology #ArachidonicAcid #Pathways #COX #Prostaglandins #Prostacyclins #Leukotrienes #Synthesis

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acid pathway and drugs ... #Pharmacology #Pathophysiology ... ArachidonicAcid #Pathways #COX ... #Leukotrienes #Synthesis ... Text: Clinical Pharmacology
Antiplatelet Drugs and their Actions

- Amy Chung, MD, MSc
@AmyChung

#Antiplatelet #Medications #Pharmacology #Pathophysiology #Drugs #Agents #COX #GIIbIIIa
Antiplatelet Drugs ... #Medications #Pharmacology ... #Pathophysiology ... #Drugs #Agents ... #COX #GIIbIIIa
Drug-Induced Acute Kidney Injury - Sites of Action Along the Nephron

#DrugInduced #AcuteKidneyInjury #AKI #Nephrology #Pathophysiology #Pharmacology
Drug-Induced Acute ... AcuteKidneyInjury #AKI ... #Nephrology #Pathophysiology ... #Pharmacology
Immune Reactions and Immunosuppressant Drugs

Glucocorticoids - Inhibition of cytokine synthesis, e.g., IL-1, IL-2
Muromonab-CD3 - Monoclonal antibody
Calcineurin
Immunosuppressant Drugs ... Inhibition of cytokine synthesis ... Immunosuppressant #Drugs ... #Pharmacology # ... Pathophysiology
Mechanism of Action of Bile Acid Sequestrants
Bile Acid Sequestrants → ↓ Hepatic Bile Acid Pool →
Hepatic Bile Acid Synthesis ... Pool → ↑ HMG-CoA ... sequestration #pathophysiology ... #pharmacology #
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
Drugs that Impair ... Decreased Aldosterone Synthesis ... #Hyperkalemia #Pathophysiology ... #Pharmacology #
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... (Losartan) • Synthesis ... differential #diagnosis #pathophysiology ... #pharmacology #
Vancomycin Associated Acute Kidney Injury

 • Drug induced acute kidney injury is generally defined as a
Kidney Injury • Drug ... 24-72 hours of drug ... is related to co-morbidities ... #Vancomycin #AKI ... #pharmacology #
Antifungal Echinocandins  - Antibiotics Class Overview

Mechanism: Inhibit glucan synthesis in fungal cell wall by blocking
Inhibit glucan synthesis ... vs Candida -> Drug ... But higher MICs ... Anidulafungin #Pharmacology
Drugs with Actions on Bronchial Smooth Muscle
Bronchodilation is promoted by cAMP. Intracellular levels of cAMP can
Drugs with Actions ... the rate of its synthesis ... #SmoothMuscle #Pathophysiology ... #Pharmacology #