23 results
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
pathophysiologic causes ... With associated pulmonary ... P-ANCA): eGPA, MPA ... #differential #diagnosis ... #algorithm #rheumatology
Streptocccus Pneumoniae
Microbiology: Gram Positive, Alpha-hemolytic, Catalase Negative
Epidemiology - 10% adult carriers:
 • Most common cause of:
• Most common cause ... media • Important cause ... Exam, CXR, ENT ... Specificity of 97%) Treatment ... #diagnosis #management
Algorithm for Management of Acute Exacerbation of COPD (AECOPD)

Obtain workup for alternate diagnoses and relevant comorbidities:
Algorithm for Management ... for alternate diagnoses ... ventilated • CXR ... #COPD #AECOPD #Algorithm ... #treatment #pulmonary
Leptospirosis
Pathogen: Leptospira (interrogans, kirschneri, noguchii)
Risk Factors:
 • Occupational exposure - Farmers, ranchers, trappers, veterinarians
 • Recreational
non-productive cough, nausea ... failure • Severe pulmonary ... Leptospirosis #Leptospira #microbiology ... #diagnosis #treatment ... #management
Portopulmonary Hypertension
Presence of pulmonary arterial hypertension in a patient with portal hypertension
No other obvious causes (chronic
other obvious causes ... : mPAP > 25mmHg, ... pressure < 15mmHg TREATMENT ... - Mechanism: causes ... #management #hepatology
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
• Most common cause ... Blood cultures • CXR ... early disease) • CXR ... Lung #Abscess #pulmonary ... #management #treatment
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... common • Imaging: CXR ... - pulmonary opacities ... Renal Failure Treatment ... #management #hematology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
without other cause ... fluid balance, and CXR ... with pulmonary ... Transfusion #Reactions #hematology ... #diagnosis #comparison
Visceral Leishmaniasis - Diagnosis and Management Summary
Species: Leishmania donovani, Leishmania infantum, Leishmania chagasi
Where: South Asia, East
and Management ... Weight Loss • Can cause ... Bilirubin, ↑BUN/Cr ... #management #treatment ... infectiousdiseases #microbiology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... , dyspnea, +/- CXR ... organ damage • Treatment ... Syndrome #TLS #diagnosis ... #management #hematology