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ebm visualabstract diagnosis management pocus differential ultrasound nejm clinical nephrology algorithm cardiology causes criticalcare gallbladder treatment comparison table pulmonary pathology
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Cytomegalovirus; GBM ... atypical HUS; MPGN
Intrinsic Renal Disease - Differential Diagnosis Vascular: • Macrovascular: Renal artery occlusion, Fibromuscular disease • Microvascular: TTP/HUS,
, Amyloidosis, MPGN ... • Nephritic: RPGN ... , IgA, Alport, MPGN
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
Glomerulonephritis (MPGN ... Complement-Mediated MGPN ... , CFHR5 neph) MPGN ... Glomerulonephritis #MPGN
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Glomerulonephritis (RPGN ... ) RPGN has three ... Henoch-SchonIein Purpura Anti-GBM ... to Kidney: Anti-GBM ... involvement: Anti-GBM
Rapidly Progressive Glomerulonephritis (RPGN) - Loss of kidney function over a short period of tirne
Glomerulonephritis (RPGN ... Basement Membrane (GBM ... Linear, ribbon-like GBM ... Glomerulonephritis #RPGN
Antenatal Visits - Testing and Schedule At Every Visit: • Gestational Age • BP • Maternal Weight
, Parvovirus GDM ... Stillbirth GDM ... after - GDM ... Fetal Well-being GBS ... Rectal Swab GBS
Cryoglobulinemia Classification Types Type 1: Monoclonal IgM (rarely IgG/lgA) • Raynaud phenomenon, Digital ulcers/gangrene, Livedo reticularis, Hyperviscosity
Liver, kidney (MPGN
Kidney Biopsy - Diagnosis Algorithms 1) Normal Glomerulus by LM 2) Glomerular Crescents 3) Double Contours of GBM 4) Endocapillary
Double Contours of GBM
Acanthocyte on Urine Microscopy Not a spaceship, not a UFO, just an acanthocyte caught “flying” in dark
presentation of RPGN
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 Guide to systemic mastocytosis Criteria for diagnosis: at least 1 major and 1 minor or 3 minor
aggregates) in BM ... are atypical on BM ... release • MCs in BM ... Hypercellular BM ... criteria for MDS or MPN
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