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diagnosis algorithm differential management nephrology clinical diabetes glomerulonephritis pharmacology pathology adrenal ketoacidosis table classification comparison diabetic dka dm2 electronmicroscopy hematology
Intrinsic Renal Disease - Differential Diagnosis Vascular: • Macrovascular: Renal artery occlusion, Fibromuscular disease • Microvascular: TTP/HUS,
, Amyloidosis, MPGN ... • Nephritic: RPGN ... , IgA, Alport, MPGN
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
Glomerulonephritis (MPGN ... Mesangiocapillary GN ... Complement-Mediated MGPN ... , CFHR5 neph) MPGN ... Glomerulonephritis #MPGN
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Glomerulonephritis (RPGN ... ) RPGN has three ... Complement: Post-strep GN ... StanfordChiefs #RPGN
Rapidly Progressive Glomerulonephritis (RPGN) - Loss of kidney function over a short period of tirne
Glomerulonephritis (RPGN ... post-infectious GN ... Glomerulonephritis #RPGN
Acanthocyte on Urine Microscopy Not a spaceship, not a UFO, just an acanthocyte caught “flying” in dark
presentation of RPGN
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 Cryoglobulinemia Classification Types Type 1: Monoclonal IgM (rarely IgG/lgA) • Raynaud phenomenon, Digital ulcers/gangrene, Livedo reticularis, Hyperviscosity
Liver, kidney (MPGN
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
basement membrane; GN ... atypical HUS; MPGN
Multiple Endocrine Neoplasias (MEN syndromes) MEN I • Hyperparathyroidism • Hypercalcemia • Possible ZE syndrome • Various
Endocrine Neoplasias (MEN ... syndromes) MEN ... Galactorrhea MEN ... catecholamines MEN ... #Differential #Endocrinology
Hyperthyroidism and Thyrotoxicosis Interpretation Table - Autonomy (Graves) - Autonomy (toxic nodule) - Exogenous thyroid hormone
preformed hormone MGH ... Table #diagnosis #endocrinology
Indications for Parathyroidectomy in Primary Hyperparathyroidism • All patients with symptomatic PHPT • Serum calcium 1
Serum calcium 1 mg ... calcium > 400 mg ... function GFR < 60mL/min ... Indications #PHPT #endocrinology
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