17 results
Push Dose Pressors - Mixing Instructions.

EPINEPHRINE
Has alpha and beta 1/2 effects so it is an inopressor
Do
Epinephrine 100 mcg ... Epinephrine 10 mcg ... minutes (5-20 mcg ... the syringe is mcg ... ) #Pharmacology
Vasopressors Table 
Rough properties by Target Receptor, Heart Rate/Inotropy, Systemic Vascular Resistance, Cardiac Output, Blood Pressure,
Dobutamine 2-20 mcg ... Isoproterenol 2-10 mcg ... Epinephrine 0-20 mcg ... Dopamine, low 1-4 mcg ... Properties #Table #Pharmacology
Vasopressors and Inotropes - Pharmacology Summary
Vasopressors
Phenylephrine (alpha-1)
 • Increases BP, SVR
 • Risk of reflex bradycardia
and Inotropes - Pharmacology ... activation • D1 (1-2 mcg ... mild alpha (5-10 mcg ... CO • a (>10 mcg ... Vasopressors #Inotropes #Pharmacology
Approach to ECGs
Check
 - Age, gender, name
 - 25mm/s; 10mm/mV
 - 1mm = 40ms; 0.1 mV
Rate
Approach to ECGs ... II - LAD: Inf Ml ... Short QT <300-360 ms ... #Approach #ECG ... #EKG #diagnosis
IBD Therapeutic Drug Monitoring Thresholds
 - Infliximab > 7 mcg/ml
 - Adalimumab > 8 mcg/ml
 -
Infliximab > 7 mcg ... > 8 mcg/ml - Certolizumab ... > 15 mcg/ml - ... > 14 mcg/ml - ... gastroenterology #pharmacology
A practical guide to starting levothyroxine therapy
Calculate full replacement dose: 1.6 mcg/kg/day
Young, otherwise healthy patient:
 •
replacement dose: 1.6 mcg ... Start at 25-50 mcg ... endocrinology #pharmacology
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
• Increased EC ... • Exogenous (KCL ... pathophysiology #pharmacology
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
concentration: > 750ng/mL ... probably < 1500ng/mL ... malabsorption) if < 200ng/mL ... Special cases (e.g ... #rheumatology #pharmacology
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... initiate if eGFR < 45 mL ... continue if eGFR < 30 mL ... side effects (e.g ... #Metformin #Pharmacology
SGLT2 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
SGLT2 Inhibitors - Pharmacology ... Contraindications: eGFR < 30 mL ... GU infections (e.g ... SGLT2 #Inhibitors #Pharmacology