12 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... is of B-cell lineage ... marrow • Mature B-cell ... involvement • T-cell ... #Hematology #Oncology
Diffuse large B cell lymphoma (DLBCL) - Management and Treatment Algorithm

By Matthew Ho, MD PhD @MatthewHoMD

#Diffuse
Diffuse large B cell ... Algorithm By ... Diffuse #large #Bcell ... #Algorithm #oncology ... #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... microglobulin Treatment ... #Chronic #Lymphocytic ... #workup #oncology ... #hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
CD10 - T-cell ... - CD7, CD3 Chronic ... Cells - B-cell ... Amy Chung, MD, MSc ... Blood #Disorders #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Chronic Lymphocytic ... Leukemia (CLL) ... Transformation to large cell ... #Leukemia #oncology ... #hematology #hemeonc
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
transformation to acute leukemia ... Allogeneic stem cell ... only curative treatment ... Diagnosis #Management #treatment ... #hematology #oncology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
common - T Cell ... ~10% - B-Cell ... Treated Like Acute Leukemias ... Amy Chung, MD, MSc ... pathophysiology #Hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... low red blood cell ... Marrow Failure • Chronic ... Syndromes #diagnosis #hematology ... #oncology
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Differential Diagnosis Algorithm ... Better call hematology ... normal/high - Chronic ... you’ll do a good workup ... #workup #hematology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
full infectious work-up ... days → add fungal work-up ... syndrome): - Hematologic ... Usually myeloid leukemias ... ± tocilizumab; call