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diagnosis differential hematology management causes oncology risk endocrinology pharmacology stratification algorithm anticoagulation cardiology comparison diabetes hasbled inhibitors lymphadenopathy nejm perioperative
Thresholds for Transfusion of Platelets in Adults Major surgery or invasive procedure, no active bleeding - ≤
Platelets in Adults Major ... procedure, no active bleeding ... Surgery with active bleeding ... 100 (rarely) Stable ... nonbleeding - < 10 Stable
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 HAS-BLED Score - Risk of Major Bleeding in 1 Year Characteristics (1 point each) • Hypertension: Baseline
Score - Risk of Major ... Bleeding in 1 Year ... • History Of major ... bleeding • Unstable ... Of antiplatelet meds
HAS-BLED Score - Hypertension: Baseline SBP > 160mmHg - Renal disease: Cr > 2.6mg/dL, on HD,
- History of major ... bleeding - Unstable ... of antiplatelet meds ... #Risk #Score #Bleeding
Lymphadenopathy - Differential Diagnosis Algorithm Localized: • Cervical: EBV, CMV, HIV, Toxo, TB, Lymphoma, Head /
• Cervical: EBV ... , CMV, HIV, Toxo ... Infection: Acute HIV ... , EBV, Mycobacterial ... Anti-epileptic drugs (AEDs
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care TRICC - NEJM 1999 -
Major Clinical Trials ... - NEJM 2011 - Hip ... /vmoitra) #EBM
Selected Treatments for Hip Fracture. Panel A shows internal fixation with multiple screws for a nondisplaced
Treatments for Hip ... with a sliding hip ... recommended for stable ... hemiarthroplasty and a total hip ... Management #Ortho #EM
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓) of cytochrome p450 CYP3A4 and P-glycoprotein. DOACs are substrates
DOACs thereby leading ... metabolization leading ... reported to have major ... reported to have major ... #Interactions #Table
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Infectious • EBV ... • CMV • HIV ... Leukemia - History of Bleeding
DPP-4 Inhibitors - Pharmacology Summary Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
inactivates GLP-1 and GIP ... Januvia) - Once/day tablet ... Onglyza) - Once/day tablet ... Tradjenta) - Once/day tablet ... Major Advantages
Interphalangeal Joint Dislocation Interphalangeal joint dislocations almost always occur dorsally, look for associated avulsion fractures! Here's a
• PIP joints are ... usually dorsal • DIP ... and PIP joints ... dislocation, due to EDS ... MH/CCF/CWRU EM
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