984 results
Osteoporosis: Pathogenesis and risk factors

 • Age > 30 (post-peak bone mass)
 • Post-menopausal women ->
estrogen • Bone malignancies ... pathophysiology #signs #symptoms
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
(Cold-induced symptoms ... Hemoglobinuria • Symptoms ... • Underlying malignancies ... - B-cell malignancies ... rewarming • Symptoms
Fever of Unknown Origin (FUO) - Further Workup

 • CNS symptoms? Get an LP and imaging
Workup • CNS symptoms ... supporting hematologic malignancies
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings

Medical Comorbidities Malignancies (most commonly hairy-cell leukemia)
Immunogenetic Predisposition: patient is
Comorbidities Malignancies ... Diagnosis #Signs #Symptoms
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
- B symptoms ... Nodal disease: B symptoms ... Diagnosis of B-Symptoms ... Other hematologic Malignancies
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Hematological malignancies ... autoantibodies #signs #symptoms
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
PBC Signs and Symptoms ... and solid organ malignancies
Hyperthyroidism Overview

Clinical Manifestation of Hyperthyroidism:
 • Fatigue
 • Weight loss
 • Heat intolerance
 • Depression, nervousness
Follicular CA • Malignancies ... endocrinology #signs #symptoms
Vancomycin induced Leukocytoclastic Vasculitis (LCV) of the Hand
70 M vertebral osteomyelitis on vancomycin and cefepime for
eosinophilia and systemic symptoms ... diseases, and malignancies
Protein Losing Enteropathy
Clinical Presentation:
 • Volume overload: Peripheral edema, pleural effusion or ascites.
 • Gl symptoms
• Gl symptoms ... : UC/Crohn, Gl malignancies