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differential algorithm hemeonc leukemia lymphocytic mds myelodysplastic allergy apml ascites classification common cvid differentiation emergencies hemophagocytic hepatitis hlh hodgkins hypogammaglobulinemia
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... Kawasaki, Nephrotic syndrome ... • Infections: Chronic ... #Algorithm #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Diagnosis: • ... #Leukemia #diagnosis ... #workup #oncology ... #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... and Management ... Allogeneic stem cell ... Myelodysplastic #Syndrome ... #hematology #oncology
Tumor Lysis Syndrome An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... chemosensitive malignancy ... Walid Malki, MD, MS ... #TLS #oncology ... #management #UricAcid
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... uw_IMresidency #CLL ... #Leukemia #oncology ... #hematology #hemeonc ... #diagnosis #management
Approach to Elevated Tryptase - Differential Diagnosis Framework The DDx of elevated tryptase can be broken down
- Differential Diagnosis ... Causes: • Mast cell ... activation syndrome ... malignancy ... #hematology #allergy
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Marrow Failure • Chronic ... Workup: • Complete ... #diagnosis #hematology ... #oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... • Induce blast cell ... Differentiation #Syndrome ... #management #hematology ... #oncology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
antibiotics TLS ... ): - Hematologic ... low Ca - q8 h TLS ... Hypercalcemia of malignancy ... #HemeOnc #Diagnosis
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