22 results
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Diagnosis: • Peripheral ... Complications: 1) Infection ... chemotherapy for low-risk disease ... #Leukemia #oncology ... #diagnosis #management
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm
No Objective Weakness
 • Cardio-pulmonary disease
Causes of Peripheral ... Weakness • Cardio-pulmonary ... diseaseAnemia ... Lambert-Eaton Myasthenic Syndrome ... #Weakness #Neurology
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Hematuria, Hemoptysis, Peripheral ... symptomatology Differential ... allopurinol), Infection ... #differential # ... diagnosis #nephrology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
weeks without infection ... cytometry • Peripheral ... cells can indicate disease ... • Neutropenia, anemia ... microglobulin Treatment
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Diagnosis Algorithm Peripheral ... hemolysis, deficiency anemia ... Rebound effect from treatment ... Vasculitides, IBD, Celiac disease ... Kawasaki, Nephrotic syndrome
Etiologies of Peripheral Neuropathy
 • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism
 • Medication-induced: ART, Antibiotics,
Etiologies of Peripheral ... Chemotherapy • Infectious ... Paraprotein-associated (POEMS syndrome ... #Neuropathy #differential ... diagnosis #causes #neurology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... develop leukostasis syndrome ... - infiltrates (anemia ... • Tumor lysis syndrome ... #Oncology #Diagnosis
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Idiopathic • Infections ... ) Labs: • Peripheral ... Treatment: ... #oncology #hematology ... #diagnosis #management
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Pulmonary ... - SLE Neurologic ... • Peripheral ... #joint #pain #differential ... #diagnosis #rheumatology
Hematuria in Post-Renal Transplant Patient
Prevalence up to 12% in the postrenal transplant patient
 • Bacterial: Escherichia
: Secondary to infections ... , Busulfan • Disease ... (Goodpasture's syndrome ... #blood #urine #management ... #treatment #nephrology