209 results
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome - Treatment ... Ulcers: • Treatment ... Skin manifestations ... : • Most manifestations ... #management #pharmacology
Leptospirosis
Pathogen: Leptospira (interrogans, kirschneri, noguchii)
Risk Factors:
 • Occupational exposure - Farmers, ranchers, trappers, veterinarians
 • Recreational
Presentation: • Mild disease ... non-productive cough, nausea ... Severe pulmonary disease ... exposure + clinical manifestations ... microbiology #diagnosis #treatment
ILD of Known Cause - Differential Diagnosis
Exposure:
 • Occupational: Asbestosis, Silicosis, Hypersensitivity, Pneumonitis
 • Treatment Related:
ILD of Known Cause ... Pneumonitis • Treatment ... Connective Tissue Disease ... BrighamChiefs #ILD #Causes ... interstitial #lung #disease
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
10% of all lupus cases ... constitutional symptoms • Treatment ... Discontinuation of causal ... life-threatening • Treatment ... Evolution: Chronic disease
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... SLE) Clinical Manifestations ... Cerebrovascular Disease ... autoantibodies that will cause ... Puncture, EEG Treatment
Initial treatment of renal bone disease and cinacalcet for secondary hyperparathyroidism
Phosphate binders reduce hyperphosphataemia and hyperparathyroidism.
Initial treatment ... of renal bone disease ... the first-line treatments ... #Pharmacology #Pathophysiology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
1 • Clinical Manifestations ... • Laboratory Manifestations ... Positive in 60-80% of cases ... life-threatening • Treatment ... Evolution: Chronic disease
Treatment of Wilson's Disease
 • D-penicillamine - Chelator, induces cupruria
 • Trientine - Chelator, induces cupruria
Treatment of Wilson's ... Disease • D-penicillamine ... copper #Wilsons #Disease ... #Treatment #management ... #pharmacology
Hansen's Disease (Leprosy)
 • Transmission - not completely understood, ?nasal droplets
 • Symptoms appear ~5 years
Hansen's Disease ... do not contract disease ... Histopathologic Manifestations ... and numerous AFB Treatment ... diagnosis #management #treatment
Perianal Crohn's Disease - IBD Algorithm

 • 5-40% w perianal fistula
 • ↑ risk if colonic
Perianal Crohn's Disease ... CD • Initial manifestation ... Perianal #Crohns #Disease ... gastroenterology #management #treatment