3097 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... Summary myelo (marrow ... funny-shaped cells in the marrow ... • Bone marrow ... acute leukemia Management
Multiple Myeloma Diagnosis and Management Summary
Clinical Signs:
 • hyperCalcemia 28% (bone demineralization)
 • Renal disease 48%
Diagnosis and Management ... Anemia 78% (bone marrow ... - Clonal bone marrow ... clonal cell in bone marrow ... Myeloma #Diagnosis #Management
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Hypocellular bone marrow ... Direct Damage to Marrow ... MDS: • ↓ bone marrow ... EPO Level ↑ • Marrow ... hematology #diagnosis #management
Suggested algorithm for bone marrow biopsy and skeletal imaging in patients with monoclonal gammopathy of undetermined
algorithm for bone marrow ... MGUS) A bone marrow ... algorithm #diagnosis #management
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
hypocellular bone marrow ... Anemia #diagnosis #management
Evans Syndrome Pharmacology Management 
Corticosteroids
IVIg
Rituximab
Splenectomy
Azathioprine
Cyclophosphamide
Cyclosporin
Mycophenolate
Vinka-alkaloid
Plasma exchange
Transfusion
Anticoagulation
Bone marrow stimulating agents

doi:10.3390/jcm9123851

#Evans #Syndrome #Pharmacology #Management #Medications #comparison #table
Syndrome Pharmacology Management ... Anticoagulation Bone marrow ... #Pharmacology #Management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
hemophagocytosis in the bone marrow ... staining of bone marrow ... found in the bone marrow ... Syndrome #Diagnosis #Management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Biological + Bone Marrow ... ↑ LDH • Bone marrow ... Lymphohistiocytosis #diagnosis #management
Visceral Leishmaniasis - Diagnosis and Management Summary
Species: Leishmania donovani, Leishmania infantum, Leishmania chagasi
Where: South Asia, East
Diagnosis and Management ... Diagnosis: Bone marrow ... Leishmaniasis #diagnosis #management
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
Diagnosis and Management ... Hypercellular bone marrow ... PV #Diagnosis #Management