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diagnosis management algorithm causes cll leukemia lymphocytic rheumatology thrombocytosis abscess adultonset alkaline alp aplastic calculation cardiology ck classification creatine disease
Iron Panel Interpretation Iron deficiency - ↓ Iron, ↑-nl Transferrin / TIBC, ↓ Transferrin Saturation, ↓
, ↓ Ferritin Anemia ... of chronic inflammation ... + Chronic inflammation ... #diagnosis #differential ... #hematology #laboratory
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
x (Hct / 45) / Maturation ... Factor The maturation ... , G6PD deficiency ... Production #Index #hematology ... #anemia #differential
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Thrombocytosis - Differential ... effect following treatment ... malignancy • Iron deficiency ... anemia #Thrombocytosis ... #Differential #
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... Acute hemolysis, deficiency ... anemia, Rebound ... effect from treatment ... • Infections: Chronic
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... immunophenotype Clinical ... 5) Symptoms of anemia ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Creatine Kinase - Causes of Elevated CK Levels Acute CK Elevation (Pain > Weakness): • RHABDOMYOLYSIS
immobility • Critical ... exercise Subacute to Chronic ... - Vit D/E deficiency ... daptomycin - Chronic ... #differential #
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... , GATA2 deficiency ... , CTLA4 deficiency ... Treatment: ... #oncology #hematology
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology Pulse pressure is the difference between the systolic blood
Diagnosis and Pathophysiology ... • Severe iron deficiency ... anemia (reduced ... disorders - Chronic ... Worse outcomes in CKD
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... fraction < 20% Differential ... mevalonate kinase deficiency ... diagnosis #management #treatment ... #rheumatology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Phosphatase Of Clinical ... thigh bones -> chronic ... • Pernicious anemia ... collection with EDTA Pathophysiology ... Hyophosphatasia #hepatology
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