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diagnosis causes algorithm approach calculation cd4 icl idiopathic index lymphopenia management mds mycobacteria myelodysplasia myelodysplastic nontuberculous ntm pancytopenia production reticulocyte
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm Sequestration: • Splenomegaly Marrow Infiltration: • Hematologic and non-hematologic
malignancies • Infection ... • Toxins • Aplastic ... Anemia • Myelodysplasia ... Nutritional deficiency ... Algorithm #Causes #Hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
- Differential ... Non-hemolytic: ACD, Aplastic ... Macroangiopathic, Infections ... #Differential # ... Diagnosis #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential ... Reticulocytes, MCV ... • Aplastic Anemia ... #Classification ... Algorithm #Causes #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Corpuscular Volume (MCV ... ) - Differential ... Inflammation, Chronic Infection ... #MCV #Classification ... Algorithm #Causes #Hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Difficulty breathing • Neutropenia ... #Anemia #oncology ... #hematology #diagnosis
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
x (Hct / 45) / Maturation ... Factor The maturation ... marrow failure: Aplastic ... Production #Index #hematology ... #anemia #differential
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
- Differential ... Megaloblastic anemia-rare ... - Copper deficiency-rare ... white blood cell aplasia ... diagnosis #causes #hematology
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia DIAGNOSTIC CRITERIA FOR ICL • Persistent CD4 T-cell lymphopenia •
Heme (lymphoma. aplasia ... myelodysplasia) • Infections ... variable immune deficiency ... ICL #diagnosis #hematology ... #Differential #
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
• Aplastic Anemia ... Myeloproliferative Disease • Neutropenia ... blood count with differential ... Syndromes #diagnosis #hematology ... #oncology
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Hematologic malignancy ... Bone Marrow - Anemia ... , neutropenia ... #differential # ... diagnosis #infectiousdiseases
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