13 results
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm
Sequestration:
 • Splenomegaly
Marrow Infiltration:
 • Hematologic and non-hematologic
Causes of Neutropenia ... Diagnosis Algorithm ... malignancies • Infection ... Toxins • Aplastic Anemia ... Myelodysplasia Nutritional deficiency
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
) - Differential ... Diagnosis Algorithm ... Inflammation, Chronic Infection ... #MCV #Classification ... #Causes #Hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
Algorithmic Approach ... to Anemia - Differential ... Macroangiopathic, Infections ... #MCV #Algorithm ... Diagnosis #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
- Differential ... Diagnosis Algorithm ... Reticulocytes, MCV ... #Classification ... #Causes #Hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Diagnosis Algorithm ... Pseudotumor - Infectious ... • EBV • CMV ... #Causes #Hematology ... #Oncology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Diagnosis Algorithm ... Chronic Myelogenous Leukemia ... Myelofibrosis Infectious ... malignancy • Iron deficiency ... anemia #Thrombocytosis
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Diagnosis Algorithm ... Megakaryopoiesis • Aplastic Anemia ... Leukemia, Tumour ... Vasculitis • Infection ... #Causes #Hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Difficulty breathing • Neutropenia ... , GATA2 deficiency ... , CTLA4 deficiency ... virus (EBV) • Leukemia ... #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Malaise, bleeding, infections ... all phases of maturation ... - infiltrates (anemia ... or functional neutropenia ... #Hematology #Oncology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
., HIV), EBV infection ... involved) • No leukemic ... translocation • Types: Classification ... NonHodgkins #comparison #oncology ... #hematology