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causes algorithm dermatology rheumatology management classification oncology hemolytic secondary workup skinrash clinical disease hepatology iron rash systemic alopecia hairloss hemolysis
Iron Panel Interpretation Iron deficiency - ↓ Iron, ↑-nl Transferrin / TIBC, ↓ Transferrin Saturation, ↓
Interpretation Iron deficiency ... , ↓ Ferritin Anemia ... Ferritin Iron deficiency ... #diagnosis #differential ... #hematology #laboratory
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
x (Hct / 45) / Maturation ... Factor The maturation ... Production #Index #hematology ... #anemia #differential ... #diagnosis #calculation
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm Sequestration: • Splenomegaly Marrow Infiltration: • Hematologic and non-hematologic
Pancytopenia - Differential ... Diagnosis Algorithm ... malignancies • Infection ... Toxins • Aplastic Anemia ... Myelodysplasia Nutritional deficiency
Thrombocytosis - Differential Diagnosis Platelet Count > 450 Reactive: • Anemia/blood loss (Fe deficiency) • Infection/Sepsis • Non-infectious
Diagnosis Platelet ... Reactive: • Anemia ... blood loss (Fe deficiency ... ) • Infection/ ... #Platelets #hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
- Differential ... Diagnosis Framework ... Macroangiopathic, Infections ... MCV #Algorithm #Differential ... #Diagnosis #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Volume (MCV) - Differential ... Diagnosis Algorithm ... Inflammation, Chronic Infection ... #Diagnosis #Algorithm ... #Causes #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Thrombocytosis - Differential ... Diagnosis Algorithm ... Myelofibrosis Infectious ... malignancy • Iron deficiency ... anemia #Thrombocytosis
Anemia - Underproduction Diagnostic Algorithm - Iron deficiency anemia - Anemia of chronic inflammation - Anemia
Diagnostic Algorithm ... - Iron deficiency ... and/or folate deficiency ... Underproduction #Algorithm #hematology ... #diagnosis #differential
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
- Differential ... Diagnosis Algorithm ... Hypersplenism, Infection ... #Differential # ... #hematology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Pancytopenia - Differential ... Diagnosis Congenital ... • Fanconi’s anemia ... Infections: ... #Diagnosis #Hematology
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