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diagnosis hemolytic algorithm classification extravascular agglutinin atlas cirrhosis cold deficiency dermatology disease ferritin hodgkins iron key leukemia lymphoma management mds
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Causes Intravascular ... anemia): ... #Hemolytic #Intravascular ... #Causes #differential ... #diagnosis #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Hemolysis - Differential ... anemia • ... #Algorithm #Causes ... #Hematology
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
- Differential ... • Iron loss: Intravascular ... ) hemolysis, Intensive ... Gastrectomy, WHDA syndrome ... Algorithm #ferritin #hematology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... IVIG infusion Intravascular ... #Anemia #Differential ... classification #hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Myelodysplastic syndrome ... uremic syndrome ... , Disseminated intravascular ... key #diagnosis #differential ... #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
- Differential ... malignancies • Anemia ... iron deficiency, hemolysis ... Myelodysplastic syndrome ... #hematology #secondary
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
result in severe anemia ... reflection of intravascular ... anemia Indirect ... WBC count and differential ... Diagnosis #Workup #Hematology
Causes of Anemia in Cirrhosis - Differential Diagnosis Framework LOW RETIC INDEX - ↓ PRODUCTION • Vitamin
Causes of Anemia ... in Cirrhosis - Differential ... Destruction: Zieve's syndrome ... anemia, Hemolysis ... #Diagnosis #Hepatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... anemia • Cold ... younger pts) Differential ... the RBCs causing intravascular ... #anemia #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... DIC/TTP/HUS - Hemolytic ... anemia - Splenomegaly ... Kasabach-Merritt syndrome ... #Diagnosis #hematology
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