62 results
Iron Panel Interpretation

Iron deficiency - ↓ Iron, ↑-nl Transferrin / TIBC, ↓ Transferrin Saturation,  ↓
↓ Transferrin Saturation ... nl Transferrin Saturation ... ↓ Transferrin Saturation ... nl Transferrin Saturation ... #differential #hematology
Causes of Hyperferritinemia - Differential Diagnosis
Ferritin > 1000
Ferritin is the storage form of iron. Increased hepcidin
storage form of iron ... absorption of iron ... Iron overload - ... Hematologic Malignancy ... Check the iron saturation
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Causes of Thrombocytosis ... Non malignant hematologic ... malignancy • Iron ... Diagnosis #Algorithm #Causes ... #Hematology
Iron Deficiency in Heart Failure
Pathophysiology:
Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Iron Deficiency ... Heart Failure Pathophysiology ... → Inflammation causes ... absorption and iron ... endpoint of all-cause
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
out additional causes ... evaluation for other causes ... including liver and hematologic ... If other causes ... saturation.
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased Heme Synthesis or
Causes of Anemia ... MCV/RBC>13 • Iron ... Deficiency (Eg Causes ... Diagnosis #Algorithm #Causes ... #Hematology
Causes of Polycythemia (Erythrocytosis) - Differential Diagnosis Algorithm
Relative - Normal RBC Mass / Decreased Plasma Volume
Causes of Polycythemia ... Erythropoietin, O2 Saturation ... Hemoglobin - O2 Saturation ... Diagnosis #Algorithm #Causes ... #Hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
x (Hct / 45) / Maturation ... Factor The maturation ... deficiencies: Iron ... Production #Index #hematology
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Causes of Thrombocytosis ... (specifically: iron ... Differential #Diagnosis #Causes ... #hematology #secondary
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
MCH, MCHC, Serum Iron ... Reticulocytes • Iron ... Diagnosis #Algorithm #Causes ... #Hematology