23 results
Iron Panel Interpretation

Iron deficiency - ↓ Iron, ↑-nl Transferrin / TIBC, ↓ Transferrin Saturation,  ↓
↓ Transferrin Saturation ... , ↓ Ferritin Anemia ... nl Transferrin Saturation ... #differential #hematology ... #laboratory
Iron Deficiency Anemia vs Anemia of Chronic Disease - Laboratory Testing

SUMMARY:
 - RDW, FEP, serum iron,
of Chronic Disease ... - Laboratory Testing ... , saturation-worthless ... #Chronic #Disease ... #Laboratory #Testing
Causes of Iron Deficiency
 • Diet: ↓ Intake, e.g. vegan, Malnutrition, Polyphenol / tannins, ↓ Vitamin
Causes of Iron Deficiency ... : IBD, Chronic disease ... #Deficiency #Causes ... differential #diagnosis #anemia ... #nutrition
Causes of Iron Deficiency
 • Inadequate Intake: Vegetarian/vegan diet, Malnutrition
 • Increased Body Needs: Infants/preschoolers, Pregnancy,
Causes of Iron Deficiency ... Loss (without anaemia ... Edema, Celiac disease ... IBD, cancer) #Iron ... #nutrition
Causes of False Elevation and Reduction in HbA1c

== False Elevation ==
Decreased RBC turnover 
• Iron, B-12,
Causes of False ... RBC turnover • Iron ... • Asplenia Laboratory ... • Hemolytic anemia ... End-stage renal disease
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Causes of Anemia ... Volume (<80 fL) • Iron ... Poisoning • Anemia ... Diagnosis #Algorithm #Causes ... #Hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
x (Hct / 45) / Maturation ... Factor The maturation ... deficiencies: Iron ... Chronic kidney disease ... Production #Index #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
MCH, MCHC, Serum Iron ... Reticulocytes • Iron ... Disease • Marrow ... Diagnosis #Algorithm #Causes ... #Hematology
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
secondary to Systemic Diseases ... Spoon-shaped • Iron ... deficiency anemia ... Systemic #Secondary #dermatology ... Diagnosis #Algorithm #causes
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
Microcytic" • Iron ... chronic kidney disease ... Alcohol use, Liver disease ... differential #diagnosis #causes ... #hematology