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diagnosis differential hematology signs algorithm deficiency gastroenterology management celiac testing cardiology causes chronic hepatology oncology rheumatology workup agammaglobulinemia alcohol alcoholism
Iron Deficiency Anemia vs Anemia of Chronic Disease - Laboratory Testing SUMMARY: - RDW, FEP, serum iron,
of Chronic Disease ... - Laboratory Testing ... , saturation-worthless ... #Chronic #Disease ... #Laboratory #Testing
Iron Panel Interpretation Iron deficiency - ↓ Iron, ↑-nl Transferrin / TIBC, ↓ Transferrin Saturation, ↓
↓ Transferrin Saturation ... , ↓ Ferritin Anemia ... nl Transferrin Saturation ... ↓ Transferrin Saturation ... differential #hematology #laboratory
For an elderly patient with multiple comorbidities it can be challenging to determine if their anemia
determine if their anemia ... is secondary to iron ... of chronic disease ... benefit from IV iron ... #Transferrin #Saturation
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
RBC turnover • Iron ... • Asplenia Laboratory ... • Hemolytic anemia ... End-stage renal disease ... HbA1c #HgbA1c #Laboratory
Gastrointestinal Evaluation of Iron Deficiency Anemia In patients with anemia, diagnose iron deficiency if: • Ferritin <
Deficiency Anemia ... patients with anemia ... • Additional laboratory ... Test for celiac disease ... #Deficiency #Anemia
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
x (Hct / 45) / Maturation ... Factor The maturation ... Index < 2: • Anemia ... deficiencies: Iron ... Chronic kidney disease
Suspected Celiac Disease - Diagnosis Algorithm Celiac disease suspected: • Signs and symptoms of celiac disease •
Suspected Celiac Disease ... • Signs and symptoms ... of celiac disease ... • Iron-deficiency ... anemia unresponsive
Anaplasma Infection - Anaplasma phagocytophilum Pathophysiology: • Obligate, intracellular bacteria • Transmitted via blacklegged tick —
phagocytophilum Pathophysiology ... morulae Signs and symptoms ... cough (30% cases) Laboratory ... immature forms) • Anemia
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
• Hemolytic Anemias ... - Pernicious anemia ... deficiency - Iron ... associated with any symptoms ... differential #diagnosis #Laboratory
Anemia of Chronic Disease - Pathophysiology One theory to explain why "anemia of chronic disease" exists: The inflammatory
Anemia of Chronic ... Disease - Pathophysiology ... often require iron ... ability to lock up iron ... #pathophysiology
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