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differential algorithm causes hepatology management oncology leukemia primary workup cholangitis classification cll dermatology laboratory rheumatology syndrome systemic alkaline alp approach
Iron Panel Interpretation Iron deficiency - ↓ Iron, ↑-nl Transferrin / TIBC, ↓ Transferrin Saturation, ↓
, ↓ Ferritin Anemia ... of chronic inflammation ... deficiency + Chronic ... Interpretation #deficiency #diagnosis ... #differential #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... minimal tumor burden Diagnosis ... marrow failure with anemia ... #oncology #hematology ... #hemeonc #diagnosis
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
x (Hct / 45) / Maturation ... Factor The maturation ... deficiencies: Iron ... Production #Index #hematology ... #diagnosis #calculation
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential Diagnosis ... RBCs on Smear • Chronic ... MCH, MCHC, Serum Iron ... • Anemia of Chronic ... Algorithm #Causes #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
- Differential Diagnosis ... Artifact (redo CBC ... : • Acute or Chronic ... malignancy • Iron ... deficiency anemia
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
, Thalassemia, Iron ... , Chronic disease ... elliptocytosis, Severe iron ... #differential #diagnosis ... #hematology #microscopy
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
- Differential Diagnosis ... RA, SLE, PRV, Chronic ... • Early Iron ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
Causes of Anemia ... - Differential Diagnosis ... (Eg Causes: Chronic ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
count ↑ PLT • ↑ PBS ... all phases of maturation ... - infiltrates (anemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary Cirrhosis ... Pathophysiology ... : • T lymphocyte ... Signs and Symptoms ... #hepatology
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