20 results
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
• Homogeneous: Systemic ... disease (MCTD), Drug-induced ... Juvenile Idiopathic Arthritis ... ANA #patterns #rheumatology ... #diagnosis #differential
Causes of Isolated Neutropenia - Differential Diagnosis Algorithm
Congenital
Medications
 • Anticonvulsants
 • Antibiotics
 • Antithyroid
 • Antihypertensive
Diagnosis Algorithm ... Congenital Medications ... Destruction • Systemic ... • Rheumatoid Arthritis ... #Causes #Hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
deficiencies: Iron ... suppression (e.g. drugs ... Production #Index #hematology ... #anemia #differential ... #diagnosis #calculation
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Spoon-shaped • Iron ... Discoloration • Medications ... #Secondary #dermatology ... #Differential # ... Diagnosis #Algorithm
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
disease (MCTD), Drug-induced ... Juvenile Idiopathic Arthritis ... , Drug-Induced Lupus ... ANA #patterns #rheumatology ... #diagnosis #differential
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Causes of Fatigue - Differential ... Diagnosis Algorithm ... Neoplastic / Hematologic ... • Rheumatoid Arthritis ... Myasthenia Gravis Pharmacologic
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Diagnosis Framework ... , HSV, VZV • Medications ... valproate, azoles), Drugs ... MDMA), Alcohol, Iron ... #Diagnosis #hepatology
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... #hyperkalemia #differential ... #diagnosis #pathophysiology ... #pharmacology # ... potassium #medications
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... : - Arthritis ... (aPL) 30-45% Differential ... Mimickers: Drug-induced ... #rheumatology
Allopecia - Differential Diagnosis Framework for Hair Loss

Localized / Focal Hair Loss Pattern:
 • Scarring Alopecia:
Allopecia - Differential ... Diagnosis Framework ... Vitamin D levels Systemic ... loss #alopecia #Differential ... #Diagnosis #dermatology