31 results
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
Hemolysis - Diagnostic ... #Hemolytic #Anemia ... #Algorithm #Differential ... #Causes #Workup ... #Hematology #Diagnosis
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Causes of Extravascular ... - Differential ... within circulation ... anemia • ... #Causes #Hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
x (Hct / 45) / Maturation ... Factor The maturation ... , G6PD deficiency ... #anemia #differential ... #diagnosis #calculation
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... lymphoproliferative disorders ... G6PD deficiency) ... #differential # ... diagnosis #hematology
Causes of Wide Pulse Pressure - Differential Diagnosis
Physiologic:
 • Advanced age-arteriosclerosis (less compliant arteries)
 • Well
Causes of Wide Pulse ... Pressure - Differential ... Diagnosis Physiologic ... - Severe iron deficiency ... Diagnosis #causes
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Consider RBC membrane disorder ... #Anemia #Differential ... #workup #hematology
Anemia - Underproduction Diagnostic Algorithm
 - Iron deficiency anemia
 - Anemia of chronic inflammation
 - Anemia
Diagnostic Algorithm ... - Iron deficiency ... Probable bone marrow disorder ... #diagnosis #differential ... #workup
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Causes of Anemia ... Volume (MCV) - Differential ... Diagnosis Algorithm ... • Early Iron Deficiency ... #Causes #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Causes of Anemia ... Volume (MCV) - Differential ... Diagnosis Algorithm ... • Bleeding • Hemolysis ... #Causes #Hematology
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
malignancies • Anemia ... specifically: iron deficiency ... , hemolysis, hemorrhage ... Chronic inflammatory disorders ... #Diagnosis #Causes