22 results
diagnosis algorithm causes management bleeding bruising syndrome thrombocytopenia dermatology disease hepatology hepatopulmonary oncology peds purpura thrombocytosis vonwillebrand workup aafp acquired
Platelet disorders and Aggregometry Glanzmann Thrombasthenia • Defective aggregation to all agonists except ristocetin • Normal platelet,
Platelet disorders ... 1 or Type 3) — differentiate ... Von Willebrand Disease ... #disorders #hematology ... #hemepath #differential
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Bleeding / Bruising - Differential ... Sequestration Disordered ... Platelet Function ... Connective Tissue Disorders ... Algorithm #Causes #Hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... RBC's secondary to platelet ... Thrombocytopenia • Platelet ... Vasculopathy #Purpura #Differential ... #Diagnosis #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Disorders - Differential ... PT, aPTT(liver disease ... bypass), LFT (liver disease ... #Disorders #Differential ... Causes #Workup #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Thrombocytosis - Elevated Platelet ... Count - Differential ... Rebound effect from treatment ... Vasculitides, IBD, Celiac disease ... #Differential #
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Thrombocytosis - Differential ... • Rheumatic disorders ... • Celiac disease ... effect following treatment ... Thrombocytosis #Differential
Von Willebrand Disease - Most common inherited bleeding disorder Clinical • Easy bruising •
Von Willebrand Disease ... inherited bleeding disorder ... Laboratory • Normal platelet ... factor VIII) Treatment ... #Diagnosis #Hematology
Platelet Disorders - Differential Diagnosis Framework Qualitative Defects: • Adhesion • Aggregation • Secretion Quantitative Defects: • Production:
Platelet Disorders ... - Differential ... , marrow disease ... #Disorders #Differential ... #Diagnosis #hematology
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Lymphoproliferative disorders ... Myeloproliferative disorders ... thrombocythemia), Autoimmune disease ... Diagnosis #Management #treatment ... #hematology #differential
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... with or without platelet ... Consider RBC membrane disorder ... Hemolytic #Anemia #Differential ... Algorithm #workup #hematology
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