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diagnosis management hematology differential lupus signs algorithm erythematosus sle symptoms causes comparison disease classification oncology workup dermatology neurology acute aflp
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Clinical Presentation ... Fever is the main clinical ... with leukopenia, anemia ... Liver function tests ... #Rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... of Systemic Lupus ... Demyelinating syndromes ... ) Blood (75%): Anemia ... symptoms #diagnosis #rheumatology
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
Diagnostic Criteria - Systemic ... Erythematosus Clinical ... Immunologic Criteria CLINICAL ... Direct Coombs’ test ... #Diagnosis #Rheumatology
Connective tissue disease-associated interstitial lung diseases LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
SSc: systemic sclerosis ... PSS: Sjogren syndrome ... arthritis SLE : systemic ... Differential #Comparison #Table ... #Pulmonary #Rheumatology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
deficiency • Fanconi’s anemia ... Wiskott-Aldrich syndrome ... Autoimmune Diseases: • Systemic ... Differential #Diagnosis #Hematology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... Initial screening test ... block • Sjogren syndrome ... polymyositis overlap syndrome ... Summary #diagnosis #rheumatology
Clinical manifestations of acute liver failure Brain: Hepatic encephalopathy, Cerebral edema, Intracranial hypertension,
Clinical manifestations ... Hepatorenal syndrome ... Lactic acidosis Systemic ... : Systemic inflammatory ... suppression, Anemia
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... Antiphospholipid Antibody Syndrome ... LAC) • Sjogren Syndrome ... • Scleroderma (Systemic ... #associations #table
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Myelodysplastic Syndromes ... Liver Function Tests ... Liver Function Tests ... Algorithm #Causes #Hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Diagnosis Algorithm - Systemic ... Skin Lesion / Systemic ... Liver Function Tests ... renal failure/uremia ... Myelodisplastic syndrome
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