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diagnosis hematology blood treatment arteritis giantcell hemophagocytic indications lymphohistiocytosis reactions transfusion 2ndline activation aortitis bloodbank classification cryoglobulinemia cryoglobulinemic differential hodgkins
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH ... Drugs, Unknown cause ... 100 mg/m2) : in case ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Cell Arteritis (GCA ... , Sarcoidosis, HLA-B27 ... (SPA) • Other Causes ... Mycobacterial Causes ... Differential #Diagnosis #rheumatology
Consensus Indications for Irradiated RBC Transfusions: Cellular blood components are irradiated for the prevention of TA-GVHD. Transfused
Individuals receiving HLA-selected ... products (e.g., ... HLA-matched, HLA ... #Indications #Hematology ... #BloodBank #Management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lymphohistiocytosis (HLH ... hypersensitivity syndromes • HLH ... Fibrin degradation products ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Treatment of giant cell arteritis (GCA) 1st Line Strategy - GC 0.7 mg/kg/day, except for: • Aortitis
cell arteritis (GCA ... MTX or TCZ in case ... giantcell #arteritis #GCA ... #Treatment #Management ... #Indications #rheumatology
Non-HCV infectious mixed cryoglobulinemia vasculitis - Diagnosis, causes and management - French Vasculitis Study Group < 5%
vasculitis - Diagnosis, causes ... and management ... infection - GCs ... Cryoglobulinemia #Vasculitis #Rheumatology ... Cryoglobulinemic #Diagnosis #Management
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Causes purpura & ... TRALI): Leading cause ... donors (due to anti-HLA ... Transfusions #diagnosis #management ... #hematology #reactions
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
cell arteritis (GCA ... cell arteritis (GCA ... identifies 85 to 95% of cases ... them, but urgent rheumatology ... Symptoms #Diagnosis #Management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
of about three cases ... Lymphoma (90-95% of cases ... genes and gene products ... classification #hematology ... #oncology #management
Hemophagocytic Lymphohistiocytosis (HLH) Treatment Primary HLH: - HLH-94 Protocol • Dexamethasone
Treatment Primary HLH ... steroids • In mild cases ... Options for severe cases ... #Treatment #management ... #hematology
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